Collagen-based products are well-known for their anti-aging effects. However, under the form of injections, the collagen products are not always easy to use. According to a new study, oral collagen has been proved to have anti-aging effects as well. This could greatly simplify the treatment protocols.
The results of the new research have been published in an article posted on the "Journal of Cosmetic Dermatology". The research team has investigated the effects on dermal collagen network and skin hydration of the orally-taken collagen peptides. According to the website skininc.com, accelerated fragmentations of the collagen network and skin dryness are among the main causes for aging of the skin.
Collagen peptides are currently used as a bioactive ingredient in anti-aging cosmetic products. The preclinical studies have shown that collagen peptides can induce the synthesis of hyaluronic acid and collagen and improve skin barrier function. This leads to promoting fibroblast migration and growth.
In the latest study, researchers used corneometry in order to analyze the effects on skin hydration of the supplementation with collagen peptides. They also used reflectance confocal microscopy, collagen fragmentation and high-resolution ultrasound in order to analyze the effects of collagen peptides on collagen density.
Human skin explants were also used in an ex vivo experiment performed in order to study the effects of the presence of collagen peptides on extracellular matrix components.
The results of the research have showed that skin hydration is increased by oral collagen peptide supplementation after eight weeks of intake. The dermal collagen network decreased and the collagen density in the dermis increased after four weeks of supplementation. The effects of collagen supplementation continued to progress after 12 weeks.
The ex vivo experiments have proved the fact that the collagen peptides supplementation can induce glycosaminoglycan and collagen production, offering an explanation for the clinical effects previously observed. The conclusion of the study is that skin aging can be delayed and prevented by oral collagen peptides supplementation.
